BDBM50412654 CHEMBL480414

SMILES: NC(=O)c1[nH]nnc1-n1nnc2cc(ccc12)-c1ccccc1

InChI Key: InChIKey=QWYRJKKVNVPOHX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel alpha/beta 1 (Homo sapiens (Human))	BDBM50412654 (CHEMBL480414) Show SMILES NC(=O)c1[nH]nnc1-n1nnc2cc(ccc12)-c1ccccc1 Show InChI InChI=1S/C15H11N7O/c16-14(23)13-15(19-20-18-13)22-12-7-6-10(8-11(12)17-21-22)9-4-2-1-3-5-9/h1-8H,(H2,16,23)(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile tone				Bioorg Med Chem 17: 319-25 (2008) Article DOI: 10.1016/j.bmc.2008.10.068 BindingDB Entry DOI: 10.7270/Q2P84D59
					More data for this Ligand-Target Pair