BDBM50413133 CHEMBL495102

SMILES: CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)N[C@H]2CC[N+](C)(Cc3ccc4OCOc4c3)C2)cc1

InChI Key: InChIKey=TXAYFVDVTWJOOE-NPQFMLNHSA-O

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50413133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50413133 (CHEMBL495102) Show SMILES CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)N[C@H]2CC[N+](C)(Cc3ccc4OCOc4c3)C2)cc1 |r| Show InChI InChI=1S/C38H40N4O6/c1-3-46-37(44)30-14-16-31(17-15-30)40-38(45)41-33(21-26-9-12-29(13-10-26)28-7-5-4-6-8-28)36(43)39-32-19-20-42(2,24-32)23-27-11-18-34-35(22-27)48-25-47-34/h4-18,22,32-33H,3,19-21,23-25H2,1-2H3,(H2-,39,40,41,43,44,45)/p+1/t32-,33-,42?/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...				Bioorg Med Chem Lett 18: 5481-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.020 BindingDB Entry DOI: 10.7270/Q23B61CM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50413133 (CHEMBL495102) Show SMILES CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)N[C@H]2CC[N+](C)(Cc3ccc4OCOc4c3)C2)cc1 |r| Show InChI InChI=1S/C38H40N4O6/c1-3-46-37(44)30-14-16-31(17-15-30)40-38(45)41-33(21-26-9-12-29(13-10-26)28-7-5-4-6-8-28)36(43)39-32-19-20-42(2,24-32)23-27-11-18-34-35(22-27)48-25-47-34/h4-18,22,32-33H,3,19-21,23-25H2,1-2H3,(H2-,39,40,41,43,44,45)/p+1/t32-,33-,42?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...				Bioorg Med Chem Lett 18: 5481-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.020 BindingDB Entry DOI: 10.7270/Q23B61CM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50413133 (CHEMBL495102) Show SMILES CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)N[C@H]2CC[N+](C)(Cc3ccc4OCOc4c3)C2)cc1 |r| Show InChI InChI=1S/C38H40N4O6/c1-3-46-37(44)30-14-16-31(17-15-30)40-38(45)41-33(21-26-9-12-29(13-10-26)28-7-5-4-6-8-28)36(43)39-32-19-20-42(2,24-32)23-27-11-18-34-35(22-27)48-25-47-34/h4-18,22,32-33H,3,19-21,23-25H2,1-2H3,(H2-,39,40,41,43,44,45)/p+1/t32-,33-,42?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...				Bioorg Med Chem Lett 18: 5481-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.020 BindingDB Entry DOI: 10.7270/Q23B61CM
					More data for this Ligand-Target Pair