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SMILES: CC(CC(=O)NC(N)=NCCCc1cnc[nH]1)c1ccccn1

InChI Key: InChIKey=YCBUFCVYAPXWON-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413175   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50413175
PNG
(CHEMBL501589)
Show SMILES CC(CC(=O)NC(N)=NCCCc1cnc[nH]1)c1ccccn1 |w:8.8|
Show InChI InChI=1S/C16H22N6O/c1-12(14-6-2-3-7-19-14)9-15(23)22-16(17)20-8-4-5-13-10-18-11-21-13/h2-3,6-7,10-12H,4-5,8-9H2,1H3,(H,18,21)(H3,17,20,22,23)
UniProtKB/SwissProt

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Similars
Article
PubMed
n/an/an/an/a 38.0n/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activity

J Med Chem 51: 7193-204 (2009)


Article DOI: 10.1021/jm800841w
BindingDB Entry DOI: 10.7270/Q2RN38T6
More data for this
Ligand-Target Pair