BDBM50413184 CHEMBL469748

SMILES: NC(NC(=O)C(c1ccccc1)c1ccccc1)=NCCCc1cnc[nH]1

InChI Key: InChIKey=IOXIWMMKUMCFIG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50413184 (CHEMBL469748) Show SMILES NC(NC(=O)C(c1ccccc1)c1ccccc1)=NCCCc1cnc[nH]1 |w:18.20| Show InChI InChI=1S/C21H23N5O/c22-21(24-13-7-12-18-14-23-15-25-18)26-20(27)19(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,14-15,19H,7,12-13H2,(H,23,25)(H3,22,24,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activity				J Med Chem 51: 7193-204 (2009) Article DOI: 10.1021/jm800841w BindingDB Entry DOI: 10.7270/Q2RN38T6
					More data for this Ligand-Target Pair