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BDBM50413243 CHEMBL472258

SMILES: COc1ccc(N(C(C)C(=O)NC2CCCC2)C(=O)c2ccccc2)c(OC)c1

InChI Key: InChIKey=QWXDWEPEAHOPQE-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413243   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))
BDBM50413243
PNG
(CHEMBL472258)
Show SMILES COc1ccc(N(C(C)C(=O)NC2CCCC2)C(=O)c2ccccc2)c(OC)c1
Show InChI InChI=1S/C23H28N2O4/c1-16(22(26)24-18-11-7-8-12-18)25(23(27)17-9-5-4-6-10-17)20-14-13-19(28-2)15-21(20)29-3/h4-6,9-10,13-16,18H,7-8,11-12H2,1-3H3,(H,24,26)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant C5a receptor in HEK cells assessed as inhibition of C5a-induced calcium mobilization


Bioorg Med Chem Lett 19: 1143-7 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.104
BindingDB Entry DOI: 10.7270/Q2Q241G1
More data for this
Ligand-Target Pair