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SMILES: COc1ccc(N(C(C(O)=O)c2ccccc2F)C(=O)c2ccccc2)c(OC)c1

InChI Key: InChIKey=TZZJPGZBPAUZGE-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413244   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor 1


(Homo sapiens (Human))		BDBM50413244
PNG
(CHEMBL513229)
Show SMILES COc1ccc(N(C(C(O)=O)c2ccccc2F)C(=O)c2ccccc2)c(OC)c1
Show InChI InChI=1S/C23H20FNO5/c1-29-16-12-13-19(20(14-16)30-2)25(22(26)15-8-4-3-5-9-15)21(23(27)28)17-10-6-7-11-18(17)24/h3-14,21H,1-2H3,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant C5a receptor in HEK cells assessed as inhibition of C5a-induced calcium mobilization

Bioorg Med Chem Lett 19: 1143-7 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.104
BindingDB Entry DOI: 10.7270/Q2Q241G1
More data for this
Ligand-Target Pair