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SMILES: Fc1c(CNC(=O)c2ccc3OCOc3c2)cccc1-c1cccc(CN2CCNCC2)c1

InChI Key: InChIKey=UUUSUGOZBNBBQR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413429   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))		BDBM50413429
PNG
(CHEMBL524031)
Show SMILES Fc1c(CNC(=O)c2ccc3OCOc3c2)cccc1-c1cccc(CN2CCNCC2)c1
Show InChI InChI=1S/C26H26FN3O3/c27-25-21(15-29-26(31)20-7-8-23-24(14-20)33-17-32-23)5-2-6-22(25)19-4-1-3-18(13-19)16-30-11-9-28-10-12-30/h1-8,13-14,28H,9-12,15-17H2,(H,29,31)
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Article
PubMed
n/an/a 2.51E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...

Bioorg Med Chem Lett 19: 1686-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.098
BindingDB Entry DOI: 10.7270/Q2639QZ5
More data for this
Ligand-Target Pair