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SMILES: O=C(NCc1cccc(c1)-c1cccc(CN2CCNCC2)c1)c1cccc(Oc2ccccc2)c1

InChI Key: InChIKey=HICIQQCYTDKJQB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413451   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))		BDBM50413451
PNG
(CHEMBL492391)
Show SMILES O=C(NCc1cccc(c1)-c1cccc(CN2CCNCC2)c1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C31H31N3O2/c35-31(28-11-6-14-30(21-28)36-29-12-2-1-3-13-29)33-22-24-7-4-9-26(19-24)27-10-5-8-25(20-27)23-34-17-15-32-16-18-34/h1-14,19-21,32H,15-18,22-23H2,(H,33,35)
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Similars
Article
PubMed
n/an/a 1.26E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...

Bioorg Med Chem Lett 19: 1686-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.098
BindingDB Entry DOI: 10.7270/Q2639QZ5
More data for this
Ligand-Target Pair