BDBM50413845 CHEMBL473705

SMILES: CN1CCC[C@@H]1C(=O)Nc1c(C)cccc1C

InChI Key: InChIKey=YEFPZQNJYCVDAB-GFCCVEGCSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4) (Homo sapiens (Human))	BDBM50413845 (CHEMBL473705) Show SMILES CN1CCC[C@@H]1C(=O)Nc1c(C)cccc1C |r| Show InChI InChI=1S/C14H20N2O/c1-10-6-4-7-11(2)13(10)15-14(17)12-8-5-9-16(12)3/h4,6-7,12H,5,8-9H2,1-3H3,(H,15,17)/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.76E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium current				Eur J Med Chem 44: 1477-85 (2009) Article DOI: 10.1016/j.ejmech.2008.10.005 BindingDB Entry DOI: 10.7270/Q2M61MGC
					More data for this Ligand-Target Pair