BDBM50413849 CHEMBL484833

SMILES: CN(C(=O)[C@H]1CCCN1C)c1c(C)cccc1C

InChI Key: InChIKey=QDARTEBYCWNHSI-CYBMUJFWSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4) (Homo sapiens (Human))	BDBM50413849 (CHEMBL484833) Show SMILES CN(C(=O)[C@H]1CCCN1C)c1c(C)cccc1C |r| Show InChI InChI=1S/C15H22N2O/c1-11-7-5-8-12(2)14(11)17(4)15(18)13-9-6-10-16(13)3/h5,7-8,13H,6,9-10H2,1-4H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.01E+5	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium current				Eur J Med Chem 44: 1477-85 (2009) Article DOI: 10.1016/j.ejmech.2008.10.005 BindingDB Entry DOI: 10.7270/Q2M61MGC
					More data for this Ligand-Target Pair