BDBM50413853 CHEMBL485004

SMILES: Cc1cccc(C)c1NC(=O)[C@@H]1CCN(Cc2ccccc2)C1

InChI Key: InChIKey=ISTWCTAZPPLWBK-GOSISDBHSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 4 subunit alpha (Homo sapiens (Human))	BDBM50413853 (CHEMBL485004) Show SMILES Cc1cccc(C)c1NC(=O)[C@@H]1CCN(Cc2ccccc2)C1 |r| Show InChI InChI=1S/C20H24N2O/c1-15-7-6-8-16(2)19(15)21-20(23)18-11-12-22(14-18)13-17-9-4-3-5-10-17/h3-10,18H,11-14H2,1-2H3,(H,21,23)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium current				Eur J Med Chem 44: 1477-85 (2009) Article DOI: 10.1016/j.ejmech.2008.10.005 BindingDB Entry DOI: 10.7270/Q2M61MGC
					More data for this Ligand-Target Pair