BDBM50413885 CHEMBL485145

SMILES: Cc1cc2c(ccnc2[nH]1)-c1ccc(NS(C)(=O)=O)cc1

InChI Key: InChIKey=WPDHZQKGFNEVJJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50413885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Homo sapiens (Human))	BDBM50413885 (CHEMBL485145) Show SMILES Cc1cc2c(ccnc2[nH]1)-c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C15H15N3O2S/c1-10-9-14-13(7-8-16-15(14)17-10)11-3-5-12(6-4-11)18-21(2,19)20/h3-9,18H,1-2H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant IKK1				Bioorg Med Chem Lett 19: 2504-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.034 BindingDB Entry DOI: 10.7270/Q2GF0VRN
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50413885 (CHEMBL485145) Show SMILES Cc1cc2c(ccnc2[nH]1)-c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C15H15N3O2S/c1-10-9-14-13(7-8-16-15(14)17-10)11-3-5-12(6-4-11)18-21(2,19)20/h3-9,18H,1-2H3,(H,16,17)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant IKK2				Bioorg Med Chem Lett 19: 2504-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.034 BindingDB Entry DOI: 10.7270/Q2GF0VRN
					More data for this Ligand-Target Pair