BDBM50414437 CHEMBL562624

SMILES: FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(Cl)c2)CC1

InChI Key: InChIKey=AZORJLGCYRQCSX-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50414437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414437 (CHEMBL562624) Show SMILES FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C17H21ClF3N3O/c18-14-2-1-3-15(12-14)24-11-10-23(16(24)25)9-8-22-6-4-13(5-7-22)17(19,20)21/h1-3,12-13H,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50414437 (CHEMBL562624) Show SMILES FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C17H21ClF3N3O/c18-14-2-1-3-15(12-14)24-11-10-23(16(24)25)9-8-22-6-4-13(5-7-22)17(19,20)21/h1-3,12-13H,4-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D2 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50414437 (CHEMBL562624) Show SMILES FC(F)(F)C1CCN(CCN2CCN(C2=O)c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C17H21ClF3N3O/c18-14-2-1-3-15(12-14)24-11-10-23(16(24)25)9-8-22-6-4-13(5-7-22)17(19,20)21/h1-3,12-13H,4-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assay				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair