BDBM50414442 CHEMBL571456

SMILES: CC(C)N1CCN(CCN2CCN(C2=O)c2cccc(c2)C#N)CC1

InChI Key: InChIKey=LVPCPZRNWKXHTK-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50414442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414442 (CHEMBL571456) Show SMILES CC(C)N1CCN(CCN2CCN(C2=O)c2cccc(c2)C#N)CC1 Show InChI InChI=1S/C19H27N5O/c1-16(2)22-9-6-21(7-10-22)8-11-23-12-13-24(19(23)25)18-5-3-4-17(14-18)15-20/h3-5,14,16H,6-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50414442 (CHEMBL571456) Show SMILES CC(C)N1CCN(CCN2CCN(C2=O)c2cccc(c2)C#N)CC1 Show InChI InChI=1S/C19H27N5O/c1-16(2)22-9-6-21(7-10-22)8-11-23-12-13-24(19(23)25)18-5-3-4-17(14-18)15-20/h3-5,14,16H,6-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D2 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50414442 (CHEMBL571456) Show SMILES CC(C)N1CCN(CCN2CCN(C2=O)c2cccc(c2)C#N)CC1 Show InChI InChI=1S/C19H27N5O/c1-16(2)22-9-6-21(7-10-22)8-11-23-12-13-24(19(23)25)18-5-3-4-17(14-18)15-20/h3-5,14,16H,6-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assay				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair