BDBM50414537 CHEMBL554297

SMILES: COc1cc(Cl)c(-c2nnc(NC(=O)c3ccc4OCCOc4c3)s2)c(Cl)c1

InChI Key: InChIKey=JNQZRPXFHPGZLH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50414537 (CHEMBL554297) Show SMILES COc1cc(Cl)c(-c2nnc(NC(=O)c3ccc4OCCOc4c3)s2)c(Cl)c1 Show InChI InChI=1S/C18H13Cl2N3O4S/c1-25-10-7-11(19)15(12(20)8-10)17-22-23-18(28-17)21-16(24)9-2-3-13-14(6-9)27-5-4-26-13/h2-3,6-8H,4-5H2,1H3,(H,21,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assay				Bioorg Med Chem Lett 19: 4292-5 (2009) Article DOI: 10.1016/j.bmcl.2009.05.074 BindingDB Entry DOI: 10.7270/Q2SQ90DS
					More data for this Ligand-Target Pair