Found 6 hits for monomerid = 50414562 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50414562
(CHEMBL554738)Show SMILES CN(CCN1CCN(C1=O)c1cccc(Cl)c1)Cc1cc2ccccc2s1 Show InChI InChI=1S/C21H22ClN3OS/c1-23(15-19-13-16-5-2-3-8-20(16)27-19)9-10-24-11-12-25(21(24)26)18-7-4-6-17(22)14-18/h2-8,13-14H,9-12,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description Antagonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043 BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50414562
(CHEMBL554738)Show SMILES CN(CCN1CCN(C1=O)c1cccc(Cl)c1)Cc1cc2ccccc2s1 Show InChI InChI=1S/C21H22ClN3OS/c1-23(15-19-13-16-5-2-3-8-20(16)27-19)9-10-24-11-12-25(21(24)26)18-7-4-6-17(22)14-18/h2-8,13-14H,9-12,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description Binding affinity to human DRD3 receptor by GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055 BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50414562
(CHEMBL554738)Show SMILES CN(CCN1CCN(C1=O)c1cccc(Cl)c1)Cc1cc2ccccc2s1 Show InChI InChI=1S/C21H22ClN3OS/c1-23(15-19-13-16-5-2-3-8-20(16)27-19)9-10-24-11-12-25(21(24)26)18-7-4-6-17(22)14-18/h2-8,13-14H,9-12,15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 50.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description Binding affinity to human DRD2 receptor by GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055 BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50414562
(CHEMBL554738)Show SMILES CN(CCN1CCN(C1=O)c1cccc(Cl)c1)Cc1cc2ccccc2s1 Show InChI InChI=1S/C21H22ClN3OS/c1-23(15-19-13-16-5-2-3-8-20(16)27-19)9-10-24-11-12-25(21(24)26)18-7-4-6-17(22)14-18/h2-8,13-14H,9-12,15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 50.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description Antagonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043 BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50414562
(CHEMBL554738)Show SMILES CN(CCN1CCN(C1=O)c1cccc(Cl)c1)Cc1cc2ccccc2s1 Show InChI InChI=1S/C21H22ClN3OS/c1-23(15-19-13-16-5-2-3-8-20(16)27-19)9-10-24-11-12-25(21(24)26)18-7-4-6-17(22)14-18/h2-8,13-14H,9-12,15H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description Displacement of [3H]dofetilide from human ERG |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055 BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50414562
(CHEMBL554738)Show SMILES CN(CCN1CCN(C1=O)c1cccc(Cl)c1)Cc1cc2ccccc2s1 Show InChI InChI=1S/C21H22ClN3OS/c1-23(15-19-13-16-5-2-3-8-20(16)27-19)9-10-24-11-12-25(21(24)26)18-7-4-6-17(22)14-18/h2-8,13-14H,9-12,15H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043 BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this Ligand-Target Pair | |