Found 6 hits for monomerid = 50414571 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50414571
(CHEMBL563563)Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(CCN1CCN(C1=O)c1cccc(Cl)c1)C2 |r| Show InChI InChI=1S/C21H30ClN3O/c1-20(2)12-18-13-21(3,14-20)15-24(18)8-7-23-9-10-25(19(23)26)17-6-4-5-16(22)11-17/h4-6,11,18H,7-10,12-15H2,1-3H3/t18-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human DRD3 receptor by GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055
BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this
Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50414571
(CHEMBL563563)Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(CCN1CCN(C1=O)c1cccc(Cl)c1)C2 |r| Show InChI InChI=1S/C21H30ClN3O/c1-20(2)12-18-13-21(3,14-20)15-24(18)8-7-23-9-10-25(19(23)26)17-6-4-5-16(22)11-17/h4-6,11,18H,7-10,12-15H2,1-3H3/t18-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description
Antagonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043
BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50414571
(CHEMBL563563)Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(CCN1CCN(C1=O)c1cccc(Cl)c1)C2 |r| Show InChI InChI=1S/C21H30ClN3O/c1-20(2)12-18-13-21(3,14-20)15-24(18)8-7-23-9-10-25(19(23)26)17-6-4-5-16(22)11-17/h4-6,11,18H,7-10,12-15H2,1-3H3/t18-,21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description
Antagonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043
BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50414571
(CHEMBL563563)Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(CCN1CCN(C1=O)c1cccc(Cl)c1)C2 |r| Show InChI InChI=1S/C21H30ClN3O/c1-20(2)12-18-13-21(3,14-20)15-24(18)8-7-23-9-10-25(19(23)26)17-6-4-5-16(22)11-17/h4-6,11,18H,7-10,12-15H2,1-3H3/t18-,21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Binding affinity to human DRD2 receptor by GTPgammaS binding assay |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055
BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50414571
(CHEMBL563563)Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(CCN1CCN(C1=O)c1cccc(Cl)c1)C2 |r| Show InChI InChI=1S/C21H30ClN3O/c1-20(2)12-18-13-21(3,14-20)15-24(18)8-7-23-9-10-25(19(23)26)17-6-4-5-16(22)11-17/h4-6,11,18H,7-10,12-15H2,1-3H3/t18-,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cancer Therapeutics
Curated by ChEMBL
| Assay Description
Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assay |
Bioorg Med Chem Lett 19: 4799-801 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.043
BindingDB Entry DOI: 10.7270/Q2154J9T |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50414571
(CHEMBL563563)Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(CCN1CCN(C1=O)c1cccc(Cl)c1)C2 |r| Show InChI InChI=1S/C21H30ClN3O/c1-20(2)12-18-13-21(3,14-20)15-24(18)8-7-23-9-10-25(19(23)26)17-6-4-5-16(22)11-17/h4-6,11,18H,7-10,12-15H2,1-3H3/t18-,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London
Curated by ChEMBL
| Assay Description
Displacement of [3H]dofetilide from human ERG |
Bioorg Med Chem Lett 19: 5056-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.055
BindingDB Entry DOI: 10.7270/Q2PR7X7C |
More data for this
Ligand-Target Pair | |
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