BDBM50414692 CHEMBL557867

SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCCCN2C(=O)c3ccccc3C2=O)CC1

InChI Key: InChIKey=LYBOUGULDAGMCU-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50414692 (CHEMBL557867) Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCCCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C26H31ClN4O4/c1-35-23-16-22(28)21(27)15-20(23)24(32)29-17-9-13-30(14-10-17)11-5-2-6-12-31-25(33)18-7-3-4-8-19(18)26(31)34/h3-4,7-8,15-17H,2,5-6,9-14,28H2,1H3,(H,29,32)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance, Inc. Curated by ChEMBL					Assay Description Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 5330-43 (2009) Article DOI: 10.1021/jm900881j BindingDB Entry DOI: 10.7270/Q2CF9RBH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50414692 (CHEMBL557867) Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCCCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C26H31ClN4O4/c1-35-23-16-22(28)21(27)15-20(23)24(32)29-17-9-13-30(14-10-17)11-5-2-6-12-31-25(33)18-7-3-4-8-19(18)26(31)34/h3-4,7-8,15-17H,2,5-6,9-14,28H2,1H3,(H,29,32)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.01	n/a	n/a	n/a	n/a
Theravance, Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assay				J Med Chem 52: 5330-43 (2009) Article DOI: 10.1021/jm900881j BindingDB Entry DOI: 10.7270/Q2CF9RBH
					More data for this Ligand-Target Pair