BDBM50414724 CHEMBL538956

SMILES: [H][C@]12CC[C@]([H])(C[C@@H](C1)NC(=O)c1cc3ccccc3n(C(C)C)c1=O)N2CCCCCCCN1CCN(CC1)C(=O)OCC

InChI Key: InChIKey=ABBXOBHUMXCOGM-PKQPGRETSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50414724 (CHEMBL538956) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)NC(=O)c1cc3ccccc3n(C(C)C)c1=O)N2CCCCCCCN1CCN(CC1)C(=O)OCC |r| Show InChI InChI=1S/C34H51N5O4/c1-4-43-34(42)37-20-18-36(19-21-37)16-10-6-5-7-11-17-38-28-14-15-29(38)24-27(23-28)35-32(40)30-22-26-12-8-9-13-31(26)39(25(2)3)33(30)41/h8-9,12-13,22,25,27-29H,4-7,10-11,14-21,23-24H2,1-3H3,(H,35,40)/t27-,28+,29-	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance, Inc. Curated by ChEMBL					Assay Description Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 5330-43 (2009) Article DOI: 10.1021/jm900881j BindingDB Entry DOI: 10.7270/Q2CF9RBH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50414724 (CHEMBL538956) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)NC(=O)c1cc3ccccc3n(C(C)C)c1=O)N2CCCCCCCN1CCN(CC1)C(=O)OCC |r| Show InChI InChI=1S/C34H51N5O4/c1-4-43-34(42)37-20-18-36(19-21-37)16-10-6-5-7-11-17-38-28-14-15-29(38)24-27(23-28)35-32(40)30-22-26-12-8-9-13-31(26)39(25(2)3)33(30)41/h8-9,12-13,22,25,27-29H,4-7,10-11,14-21,23-24H2,1-3H3,(H,35,40)/t27-,28+,29-	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.16	n/a	n/a	n/a	n/a
Theravance, Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assay				J Med Chem 52: 5330-43 (2009) Article DOI: 10.1021/jm900881j BindingDB Entry DOI: 10.7270/Q2CF9RBH
					More data for this Ligand-Target Pair