BDBM50414875 CHEMBL575915

SMILES: COc1cc2Cc3c(NCc4ccc(Cl)cc4Cl)[nH]nc3-c2cc1OC

InChI Key: InChIKey=OZPHQOYNCIJXNV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 1 (Homo sapiens (Human))	BDBM50414875 (CHEMBL575915) Show SMILES COc1cc2Cc3c(NCc4ccc(Cl)cc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H17Cl2N3O2/c1-25-16-6-11-5-14-18(13(11)8-17(16)26-2)23-24-19(14)22-9-10-3-4-12(20)7-15(10)21/h3-4,6-8H,5,9H2,1-2H3,(H2,22,23,24)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human HRI kinase				Bioorg Med Chem Lett 19: 6548-51 (2009) Article DOI: 10.1016/j.bmcl.2009.10.033 BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
					More data for this Ligand-Target Pair