BDBM50414876 CHEMBL575078

SMILES: CSc1ccc2Cc3c(NCc4c(C)cccc4Cl)[nH]nc3-c2c1

InChI Key: InChIKey=ANUAPLMOSXXXKS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 1 (Homo sapiens (Human))	BDBM50414876 (CHEMBL575078) Show SMILES CSc1ccc2Cc3c(NCc4c(C)cccc4Cl)[nH]nc3-c2c1 Show InChI InChI=1S/C19H18ClN3S/c1-11-4-3-5-17(20)16(11)10-21-19-15-8-12-6-7-13(24-2)9-14(12)18(15)22-23-19/h3-7,9H,8,10H2,1-2H3,(H2,21,22,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human HRI kinase				Bioorg Med Chem Lett 19: 6548-51 (2009) Article DOI: 10.1016/j.bmcl.2009.10.033 BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
					More data for this Ligand-Target Pair