BDBM50414878 CHEMBL575914

SMILES: COc1cccc-2c1Cc1c(NCc3c(C)cccc3Cl)[nH]nc-21

InChI Key: InChIKey=PAQYZFYUEKZBST-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 1 (Homo sapiens (Human))	BDBM50414878 (CHEMBL575914) Show SMILES COc1cccc-2c1Cc1c(NCc3c(C)cccc3Cl)[nH]nc-21 Show InChI InChI=1S/C19H18ClN3O/c1-11-5-3-7-16(20)15(11)10-21-19-14-9-13-12(18(14)22-23-19)6-4-8-17(13)24-2/h3-8H,9-10H2,1-2H3,(H2,21,22,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human HRI kinase				Bioorg Med Chem Lett 19: 6548-51 (2009) Article DOI: 10.1016/j.bmcl.2009.10.033 BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
					More data for this Ligand-Target Pair