BDBM50414884 CHEMBL573770

SMILES: Cc1cccc(Cl)c1CNc1[nH]nc-2c1Cc1cc3OCOc3cc-21

InChI Key: InChIKey=QMAHTEQOIWAAMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 1 (Homo sapiens (Human))	BDBM50414884 (CHEMBL573770) Show SMILES Cc1cccc(Cl)c1CNc1[nH]nc-2c1Cc1cc3OCOc3cc-21 Show InChI InChI=1S/C19H16ClN3O2/c1-10-3-2-4-15(20)14(10)8-21-19-13-5-11-6-16-17(25-9-24-16)7-12(11)18(13)22-23-19/h2-4,6-7H,5,8-9H2,1H3,(H2,21,22,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human HRI kinase				Bioorg Med Chem Lett 19: 6548-51 (2009) Article DOI: 10.1016/j.bmcl.2009.10.033 BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
					More data for this Ligand-Target Pair