BDBM50414888 CHEMBL583635

SMILES: COc1cc2-c3n[nH]c(NCc4c(Cl)cccc4Cl)c3S(=O)(=O)c2cc1OC

InChI Key: InChIKey=WUILAEAQNQSPNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 1 (Homo sapiens (Human))	BDBM50414888 (CHEMBL583635) Show SMILES COc1cc2-c3n[nH]c(NCc4c(Cl)cccc4Cl)c3S(=O)(=O)c2cc1OC Show InChI InChI=1S/C18H15Cl2N3O4S/c1-26-13-6-9-15(7-14(13)27-2)28(24,25)17-16(9)22-23-18(17)21-8-10-11(19)4-3-5-12(10)20/h3-7H,8H2,1-2H3,(H2,21,22,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human HRI kinase				Bioorg Med Chem Lett 19: 6548-51 (2009) Article DOI: 10.1016/j.bmcl.2009.10.033 BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
					More data for this Ligand-Target Pair