BDBM50414917 CHEMBL567004

SMILES: CCOC(=O)c1cc(-c2csc(CS(=O)(=O)c3ccccc3)n2)c(=O)[nH]c1C

InChI Key: InChIKey=DYHPOLTXTOPHPD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50414917 (CHEMBL567004) Show SMILES CCOC(=O)c1cc(-c2csc(CS(=O)(=O)c3ccccc3)n2)c(=O)[nH]c1C Show InChI InChI=1S/C19H18N2O5S2/c1-3-26-19(23)14-9-15(18(22)20-12(14)2)16-10-27-17(21-16)11-28(24,25)13-7-5-4-6-8-13/h4-10H,3,11H2,1-2H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATP				Bioorg Med Chem Lett 19: 6591-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.027 BindingDB Entry DOI: 10.7270/Q2K937KN
					More data for this Ligand-Target Pair