BDBM50415138 CHEMBL576078

SMILES: CCCc1ccccc1C(C)OC1=NCCN1

InChI Key: InChIKey=CKZOGIXOGHVXNW-UHFFFAOYSA-N

Data: 3 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50415138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50415138 (CHEMBL576078) Show SMILES CCCc1ccccc1C(C)OC1=NCCN1 |t:13| Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human alpha2A adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation counting				J Med Chem 52: 7319-22 (2009) Article DOI: 10.1021/jm901262f BindingDB Entry DOI: 10.7270/Q2J104DZ
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50415138 (CHEMBL576078) Show SMILES CCCc1ccccc1C(C)OC1=NCCN1 |t:13| Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human Alpha-2C adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation counting				J Med Chem 52: 7319-22 (2009) Article DOI: 10.1021/jm901262f BindingDB Entry DOI: 10.7270/Q2J104DZ
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50415138 (CHEMBL576078) Show SMILES CCCc1ccccc1C(C)OC1=NCCN1 |t:13| Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human alpha2B adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation counting				J Med Chem 52: 7319-22 (2009) Article DOI: 10.1021/jm901262f BindingDB Entry DOI: 10.7270/Q2J104DZ
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50415138 (CHEMBL576078) Show SMILES CCCc1ccccc1C(C)OC1=NCCN1 |t:13| Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a
Universita degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometry				J Med Chem 52: 7319-22 (2009) Article DOI: 10.1021/jm901262f BindingDB Entry DOI: 10.7270/Q2J104DZ
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50415138 (CHEMBL576078) Show SMILES CCCc1ccccc1C(C)OC1=NCCN1 |t:13| Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Universita degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human Alpha-2C adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometry				J Med Chem 52: 7319-22 (2009) Article DOI: 10.1021/jm901262f BindingDB Entry DOI: 10.7270/Q2J104DZ
					More data for this Ligand-Target Pair