BDBM50415211 CHEMBL595791

SMILES: CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1

InChI Key: InChIKey=SDOBRINCJGXIRO-HUUCEWRRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50415211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine, non-strychnine (RAT)	BDBM50415211 (CHEMBL595791) Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1 |r,THB:9:7:1:3.4| Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry				Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
					More data for this Ligand-Target Pair
Glycine, non-strychnine (RAT)	BDBM50415211 (CHEMBL595791) Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1 |r,THB:9:7:1:3.4| Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry				Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
					More data for this Ligand-Target Pair
Glycine, non-strychnine (RAT)	BDBM50415211 (CHEMBL595791) Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1 |r,THB:9:7:1:3.4| Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72.4	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry				Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
					More data for this Ligand-Target Pair