BDBM50415240 CHEMBL595737

SMILES: Cc1cc(cc2C(Nc3cncc(Cl)c3)C(=NNc12)C(N)=O)S(C)(=O)=O

InChI Key: InChIKey=LEJJTGWPKSUICL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50415240 (CHEMBL595737) Show SMILES Cc1cc(cc2C(Nc3cncc(Cl)c3)C(=NNc12)C(N)=O)S(C)(=O)=O |c:16| Show InChI InChI=1S/C16H16ClN5O3S/c1-8-3-11(26(2,24)25)5-12-13(8)21-22-15(16(18)23)14(12)20-10-4-9(17)6-19-7-10/h3-7,14,20-21H,1-2H3,(H2,18,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PDE4B catalytic domain by scintillation proximity assay				Bioorg Med Chem Lett 20: 137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.11.010 BindingDB Entry DOI: 10.7270/Q2RJ4KPG
					More data for this Ligand-Target Pair