BDBM50415243 CHEMBL605095

SMILES: CC(C)(C)S(=O)(=O)c1ccc2NN=C(C(Nc3cncc(F)c3)c2c1)C(N)=O

InChI Key: InChIKey=QFGSFKNHSXUZIM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50415243 (CHEMBL605095) Show SMILES CC(C)(C)S(=O)(=O)c1ccc2NN=C(C(Nc3cncc(F)c3)c2c1)C(N)=O |c:12| Show InChI InChI=1S/C18H20FN5O3S/c1-18(2,3)28(26,27)12-4-5-14-13(7-12)15(16(17(20)25)24-23-14)22-11-6-10(19)8-21-9-11/h4-9,15,22-23H,1-3H3,(H2,20,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PDE4B catalytic domain by scintillation proximity assay				Bioorg Med Chem Lett 20: 137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.11.010 BindingDB Entry DOI: 10.7270/Q2RJ4KPG
					More data for this Ligand-Target Pair