BDBM50415454 CHEMBL597559
SMILES: CCn1c(=O)n(Cc2cccs2)c2nc(Cc3ccco3)n(C)c2c1=O
InChI Key: InChIKey=SHCXDZDXJJTJPV-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A2b (Homo sapiens (Human)) | BDBM50415454 (CHEMBL597559) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade de Porto Curated by ChEMBL | Assay Description Displacement of [3H]DPCPX from human recombinant adenosine A2B receptor expressed in HEK293 cells by microplate beta scintillation counter | Bioorg Med Chem 18: 2001-9 (2010) Article DOI: 10.1016/j.bmc.2010.01.028 BindingDB Entry DOI: 10.7270/Q2QJ7JJ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50415454 (CHEMBL597559) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade de Porto Curated by ChEMBL | Assay Description Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO cells by microplate beta scintillation counter | Bioorg Med Chem 18: 2001-9 (2010) Article DOI: 10.1016/j.bmc.2010.01.028 BindingDB Entry DOI: 10.7270/Q2QJ7JJ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50415454 (CHEMBL597559) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 219 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade de Porto Curated by ChEMBL | Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in human HeLa cells by microplate beta scintillation counter | Bioorg Med Chem 18: 2001-9 (2010) Article DOI: 10.1016/j.bmc.2010.01.028 BindingDB Entry DOI: 10.7270/Q2QJ7JJ3 | |||||||||||
More data for this Ligand-Target Pair |