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BDBM50415493 CHEMBL589800

SMILES: CN1CCN(CC1)c1nc(NCCc2ccc(cc2)[N+]([O-])=O)c2cc(Cl)ccc2n1

InChI Key: InChIKey=NIVXGELVJXSEMX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415493   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))		BDBM50415493
PNG
(CHEMBL589800)
Show SMILES CN1CCN(CC1)c1nc(NCCc2ccc(cc2)[N+]([O-])=O)c2cc(Cl)ccc2n1
Show InChI InChI=1S/C21H23ClN6O2/c1-26-10-12-27(13-11-26)21-24-19-7-4-16(22)14-18(19)20(25-21)23-9-8-15-2-5-17(6-3-15)28(29)30/h2-7,14H,8-13H2,1H3,(H,23,24,25)
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Similars
Article
PubMed
 50.1n/an/an/an/an/an/an/an/a



Griffin Discoveries BV

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells

J Med Chem 53: 2390-400 (2010)


Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4
More data for this
Ligand-Target Pair