BDBM50415608 CHEMBL1082866

SMILES: COc1cc2CCN=C(c3ccc(F)cc3)c2cc1Cl

InChI Key: InChIKey=AUPLHCATCBBVFA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50415608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50415608 (CHEMBL1082866) Show SMILES COc1cc2CCN=C(c3ccc(F)cc3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H13ClFNO/c1-20-15-8-11-6-7-19-16(13(11)9-14(15)17)10-2-4-12(18)5-3-10/h2-5,8-9H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged p38alpha expressed in Escherichia coli by fluorescence anisotropy				Bioorg Med Chem Lett 19: 2230-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50415608 (CHEMBL1082866) Show SMILES COc1cc2CCN=C(c3ccc(F)cc3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H13ClFNO/c1-20-15-8-11-6-7-19-16(13(11)9-14(15)17)10-2-4-12(18)5-3-10/h2-5,8-9H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy				Bioorg Med Chem Lett 19: 2230-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR
					More data for this Ligand-Target Pair