BDBM50415613 CHEMBL1077137

SMILES: COc1cc2C(=NCCc2cc1Cl)c1cccc(Br)c1

InChI Key: InChIKey=NLBDGEQENFDEJW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50415613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50415613 (CHEMBL1077137) Show SMILES COc1cc2C(=NCCc2cc1Cl)c1cccc(Br)c1 |c:5| Show InChI InChI=1S/C16H13BrClNO/c1-20-15-9-13-10(8-14(15)18)5-6-19-16(13)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of histidine-tagged human recombinant p38alpha after 120 mins by TR-FRET assay				Bioorg Med Chem Lett 19: 2230-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50415613 (CHEMBL1077137) Show SMILES COc1cc2C(=NCCc2cc1Cl)c1cccc(Br)c1 |c:5| Show InChI InChI=1S/C16H13BrClNO/c1-20-15-9-13-10(8-14(15)18)5-6-19-16(13)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy				Bioorg Med Chem Lett 19: 2230-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR
					More data for this Ligand-Target Pair