BDBM50415770 CHEMBL1079516
SMILES: CNC1CN(C1)c1nc(N)nc2c1CCCC21CCCC1
InChI Key: InChIKey=FNLKLDDVROBECF-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H4 Receptor (Rattus norvegicus (rat)) | BDBM50415770 (CHEMBL1079516) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation counting | Bioorg Med Chem Lett 20: 1900-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.131 BindingDB Entry DOI: 10.7270/Q21V5G6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H4 receptor (Homo sapiens (Human)) | BDBM50415770 (CHEMBL1079516) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting | Bioorg Med Chem Lett 20: 1900-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.131 BindingDB Entry DOI: 10.7270/Q21V5G6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50415770 (CHEMBL1079516) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation counting | Bioorg Med Chem Lett 20: 1900-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.131 BindingDB Entry DOI: 10.7270/Q21V5G6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50415770 (CHEMBL1079516) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation counting | Bioorg Med Chem Lett 20: 1900-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.131 BindingDB Entry DOI: 10.7270/Q21V5G6X | |||||||||||
More data for this Ligand-Target Pair |