BDBM50415781 CHEMBL1088072

SMILES: COc1ccccc1CCCNCC1COC(O1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=YKCXYNCLHSMBJV-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50415781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50415781 (CHEMBL1088072) Show SMILES COc1ccccc1CCCNCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO3/c1-28-25-17-9-8-11-21(25)12-10-18-27-19-24-20-29-26(30-24,22-13-4-2-5-14-22)23-15-6-3-7-16-23/h2-9,11,13-17,24,27H,10,12,18-20H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in human HeLa cells				Bioorg Med Chem Lett 20: 2017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.030 BindingDB Entry DOI: 10.7270/Q2X34ZQJ
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50415781 (CHEMBL1088072) Show SMILES COc1ccccc1CCCNCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO3/c1-28-25-17-9-8-11-21(25)12-10-18-27-19-24-20-29-26(30-24,22-13-4-2-5-14-22)23-15-6-3-7-16-23/h2-9,11,13-17,24,27H,10,12,18-20H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	41.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from human Alpha-1B adrenergic receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 2017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.030 BindingDB Entry DOI: 10.7270/Q2X34ZQJ
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50415781 (CHEMBL1088072) Show SMILES COc1ccccc1CCCNCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO3/c1-28-25-17-9-8-11-21(25)12-10-18-27-19-24-20-29-26(30-24,22-13-4-2-5-14-22)23-15-6-3-7-16-23/h2-9,11,13-17,24,27H,10,12,18-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	49.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from human alpha1A adrenergic receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 2017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.030 BindingDB Entry DOI: 10.7270/Q2X34ZQJ
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50415781 (CHEMBL1088072) Show SMILES COc1ccccc1CCCNCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO3/c1-28-25-17-9-8-11-21(25)12-10-18-27-19-24-20-29-26(30-24,22-13-4-2-5-14-22)23-15-6-3-7-16-23/h2-9,11,13-17,24,27H,10,12,18-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from human Alpha-1D adrenergic receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 2017-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.030 BindingDB Entry DOI: 10.7270/Q2X34ZQJ
					More data for this Ligand-Target Pair