BDBM50415817 CHEMBL1093828

SMILES: Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1ccc(F)cc1Cl

InChI Key: InChIKey=ZHJGNHDSQQBMTR-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50415817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50415817 (CHEMBL1093828) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1ccc(F)cc1Cl Show InChI InChI=1S/C30H29ClFNO4S2/c1-20-14-21(2)30(22(3)15-20)39(36,37)33(19-26-12-13-27(32)17-29(26)31)18-23-8-10-24(11-9-23)25-6-5-7-28(16-25)38(4,34)35/h5-17H,18-19H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assay				J Med Chem 53: 3412-6 (2010) Article DOI: 10.1021/jm901797p BindingDB Entry DOI: 10.7270/Q2NP25P6
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50415817 (CHEMBL1093828) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1ccc(F)cc1Cl Show InChI InChI=1S/C30H29ClFNO4S2/c1-20-14-21(2)30(22(3)15-20)39(36,37)33(19-26-12-13-27(32)17-29(26)31)18-23-8-10-24(11-9-23)25-6-5-7-28(16-25)38(4,34)35/h5-17H,18-19H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at LXRalpha ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 ...				J Med Chem 53: 3412-6 (2010) Article DOI: 10.1021/jm901797p BindingDB Entry DOI: 10.7270/Q2NP25P6
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50415817 (CHEMBL1093828) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1ccc(F)cc1Cl Show InChI InChI=1S/C30H29ClFNO4S2/c1-20-14-21(2)30(22(3)15-20)39(36,37)33(19-26-12-13-27(32)17-29(26)31)18-23-8-10-24(11-9-23)25-6-5-7-28(16-25)38(4,34)35/h5-17H,18-19H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...				J Med Chem 53: 3412-6 (2010) Article DOI: 10.1021/jm901797p BindingDB Entry DOI: 10.7270/Q2NP25P6
					More data for this Ligand-Target Pair