BDBM50415891 CHEMBL1094744

SMILES: Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccc(Cl)cc1

InChI Key: InChIKey=RZIIKRMSNFRYPM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50415891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415891 (CHEMBL1094744) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H18Cl2FN3O/c1-12-18(13(2)26(25-12)17-7-4-15(21)5-8-17)10-20(27)24-11-14-3-6-16(23)9-19(14)22/h3-9H,10-11H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Punjabi University Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor (unknown origin)				Bioorg Med Chem 22: 54-88 (2014) Article DOI: 10.1016/j.bmc.2013.10.054 BindingDB Entry DOI: 10.7270/Q27M0BX7
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415891 (CHEMBL1094744) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H18Cl2FN3O/c1-12-18(13(2)26(25-12)17-7-4-15(21)5-8-17)10-20(27)24-11-14-3-6-16(23)9-19(14)22/h3-9H,10-11H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair