BindingDB logo
myBDB logout

null

SMILES: CNS(=O)(=O)NC[C@@H]1CCCc2cc(ccc12)S(=O)(=O)c1cccc(F)c1

InChI Key: InChIKey=VFKXXXMVYWTIPM-AWEZNQCLSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416013   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50416013
PNG
(CHEMBL1086573)
Show SMILES CNS(=O)(=O)NC[C@@H]1CCCc2cc(ccc12)S(=O)(=O)c1cccc(F)c1 |r|
Show InChI InChI=1S/C18H21FN2O4S2/c1-20-27(24,25)21-12-14-5-2-4-13-10-17(8-9-18(13)14)26(22,23)16-7-3-6-15(19)11-16/h3,6-11,14,20-21H,2,4-5,12H2,1H3/t14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1n/an/an/an/an/an/an/an/a



Roche Palo Alto LLC

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD form human recombinant 5HT6 receptor

Bioorg Med Chem Lett 20: 3436-40 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.110
BindingDB Entry DOI: 10.7270/Q2GX4CT3
More data for this
Ligand-Target Pair