BDBM50416378 CHEMBL1210563

SMILES: Cc1cnn(C)c1CC(=O)NCc1cccc(c1Cl)C(F)(F)F

InChI Key: InChIKey=CDFTXARHJMTPCB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416378 (CHEMBL1210563) Show SMILES Cc1cnn(C)c1CC(=O)NCc1cccc(c1Cl)C(F)(F)F Show InChI InChI=1S/C15H15ClF3N3O/c1-9-7-21-22(2)12(9)6-13(23)20-8-10-4-3-5-11(14(10)16)15(17,18)19/h3-5,7H,6,8H2,1-2H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair