BDBM50416392 CHEMBL1210437

SMILES: Cc1[nH]nc(c1CCC(=O)NCc1ccc(F)cc1Cl)C(C)(C)C

InChI Key: InChIKey=VSYBKDMEFJVLQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416392 (CHEMBL1210437) Show SMILES Cc1[nH]nc(c1CCC(=O)NCc1ccc(F)cc1Cl)C(C)(C)C Show InChI InChI=1S/C18H23ClFN3O/c1-11-14(17(23-22-11)18(2,3)4)7-8-16(24)21-10-12-5-6-13(20)9-15(12)19/h5-6,9H,7-8,10H2,1-4H3,(H,21,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair