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SMILES: O=C(Cc1nc(C2CCCCC2)c2ccsc2n1)NC1Cc2ccccc2C1

InChI Key: InChIKey=NJMINFKZPYIZGU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416399   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))		BDBM50416399
PNG
(CHEMBL1210642)
Show SMILES O=C(Cc1nc(C2CCCCC2)c2ccsc2n1)NC1Cc2ccccc2C1
Show InChI InChI=1S/C23H25N3OS/c27-21(24-18-12-16-8-4-5-9-17(16)13-18)14-20-25-22(15-6-2-1-3-7-15)19-10-11-28-23(19)26-20/h4-5,8-11,15,18H,1-3,6-7,12-14H2,(H,24,27)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 25.1n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human alpha7 nAChR expressed in rat GH4C1 assessed as calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 20: 4561-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.014
BindingDB Entry DOI: 10.7270/Q2959JSG
More data for this
Ligand-Target Pair