BDBM50416546 CHEMBL1215514

SMILES: NC(=O)C(Cc1ccccc1)NC(=O)c1cccc(c1)-c1cccc(O)c1

InChI Key: InChIKey=XHOIRZJBFPASOX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D Synthase (Homo sapiens (Human))	BDBM50416546 (CHEMBL1215514) Show SMILES NC(=O)C(Cc1ccccc1)NC(=O)c1cccc(c1)-c1cccc(O)c1 Show InChI InChI=1S/C22H20N2O3/c23-21(26)20(12-15-6-2-1-3-7-15)24-22(27)18-10-4-8-16(13-18)17-9-5-11-19(25)14-17/h1-11,13-14,20,25H,12H2,(H2,23,26)(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uM				J Med Chem 53: 5536-48 (2010) Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4
					More data for this Ligand-Target Pair