BDBM50416877 CHEMBL1256402
SMILES: Cc1ccc(c(C)c1)[C@@](C)(O)c1nc2ccccc2s1
InChI Key: InChIKey=IGSZVEPQZANNAB-QGZVFWFLSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcium-sensing receptor (CaSR) (Homo sapiens (Human)) | BDBM50416877 (CHEMBL1256402) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 79.4 | n/a | n/a | n/a | n/a |
ACADIA Pharmaceuticals AB Curated by ChEMBL | Assay Description Positive allosteric modulation of calcium sensing receptor by cell based assay | Bioorg Med Chem Lett 20: 5918-21 (2010) Article DOI: 10.1016/j.bmcl.2010.07.077 BindingDB Entry DOI: 10.7270/Q22J6D4S | |||||||||||
More data for this Ligand-Target Pair |