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BDBM50416879 CHEMBL1256303

SMILES: CC(O)(c1nc2ccccc2s1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=UVANBOXPVHKCGE-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416879   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))
BDBM50416879
PNG
(CHEMBL1256303)
Show SMILES CC(O)(c1nc2ccccc2s1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C15H11Cl2NOS/c1-15(19,9-6-7-10(16)11(17)8-9)14-18-12-4-2-3-5-13(12)20-14/h2-8,19H,1H3
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 100n/an/an/an/a



ACADIA Pharmaceuticals AB

Curated by ChEMBL


Assay Description
Positive allosteric modulation of calcium sensing receptor by cell based assay


Bioorg Med Chem Lett 20: 5918-21 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.077
BindingDB Entry DOI: 10.7270/Q22J6D4S
More data for this
Ligand-Target Pair