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BDBM50416881 CHEMBL1258389

SMILES: Cc1ccc(c(C)c1)C(O)(C1CC1)c1nc2ccccc2s1

InChI Key: InChIKey=PZJDSSBDEFJKFP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416881   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))
BDBM50416881
PNG
(CHEMBL1258389)
Show SMILES Cc1ccc(c(C)c1)C(O)(C1CC1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H19NOS/c1-12-7-10-15(13(2)11-12)19(21,14-8-9-14)18-20-16-5-3-4-6-17(16)22-18/h3-7,10-11,14,21H,8-9H2,1-2H3
PDB

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 200n/an/an/an/a



ACADIA Pharmaceuticals AB

Curated by ChEMBL


Assay Description
Positive allosteric modulation of calcium sensing receptor by cell based assay


Bioorg Med Chem Lett 20: 5918-21 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.077
BindingDB Entry DOI: 10.7270/Q22J6D4S
More data for this
Ligand-Target Pair