BDBM50416883 CHEMBL1255602

SMILES: Cc1cc(C)c2CCCC(O)(c3nc4ccccc4s3)c2c1

InChI Key: InChIKey=VIQVONFMEPKNOB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50416883 (CHEMBL1255602) Show SMILES Cc1cc(C)c2CCCC(O)(c3nc4ccccc4s3)c2c1 Show InChI InChI=1S/C19H19NOS/c1-12-10-13(2)14-6-5-9-19(21,15(14)11-12)18-20-16-7-3-4-8-17(16)22-18/h3-4,7-8,10-11,21H,5-6,9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals AB Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by cell based assay				Bioorg Med Chem Lett 20: 5918-21 (2010) Article DOI: 10.1016/j.bmcl.2010.07.077 BindingDB Entry DOI: 10.7270/Q22J6D4S
					More data for this Ligand-Target Pair