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SMILES: CCc1cccc(NC(=O)Nc2cc(Cl)cn(Cc3ccccc3Cl)c2=O)c1

InChI Key: InChIKey=LUBHRJTUMDADIV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417227   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))		BDBM50417227
PNG
(CHEMBL1271973)
Show SMILES CCc1cccc(NC(=O)Nc2cc(Cl)cn(Cc3ccccc3Cl)c2=O)c1
Show InChI InChI=1S/C21H19Cl2N3O2/c1-2-14-6-5-8-17(10-14)24-21(28)25-19-11-16(22)13-26(20(19)27)12-15-7-3-4-9-18(15)23/h3-11,13H,2,12H2,1H3,(H2,24,25,28)
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Similars
Article
PubMed
 501n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human EP3 receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ...

Bioorg Med Chem Lett 20: 6744-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.137
BindingDB Entry DOI: 10.7270/Q25M65Z8
More data for this
Ligand-Target Pair