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BDBM50417355 CHEMBL1278114

SMILES: OC(=O)CCNC1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21

InChI Key: InChIKey=NWCYKTKORNLIRC-BPARTEKVSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417355   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50417355
PNG
(CHEMBL1278114)
Show SMILES OC(=O)CCNC1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21 |r|
Show InChI InChI=1S/C22H25NO2/c24-21(25)10-12-23-19-9-11-22(15-19)14-18-7-2-1-5-16(18)13-17-6-3-4-8-20(17)22/h1-8,19,23H,9-15H2,(H,24,25)/t19?,22-/m0/s1
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
10n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assay


J Med Chem 53: 7778-95 (2010)


Article DOI: 10.1021/jm100856p
BindingDB Entry DOI: 10.7270/Q2FQ9WWQ
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50417355
PNG
(CHEMBL1278114)
Show SMILES OC(=O)CCNC1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21 |r|
Show InChI InChI=1S/C22H25NO2/c24-21(25)10-12-23-19-9-11-22(15-19)14-18-7-2-1-5-16(18)13-17-6-3-4-8-20(17)22/h1-8,19,23H,9-15H2,(H,24,25)/t19?,22-/m0/s1
PDB
MMDB

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UniProtKB/SwissProt

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DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.31E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from human ERG by scintillation proximity assay


J Med Chem 53: 7778-95 (2010)


Article DOI: 10.1021/jm100856p
BindingDB Entry DOI: 10.7270/Q2FQ9WWQ
More data for this
Ligand-Target Pair