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BDBM50417376 CHEMBL1278116

SMILES: CN(C)C1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21

InChI Key: InChIKey=IYDOAHOHMRQFTJ-QWAKEFERSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417376   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50417376
PNG
(CHEMBL1278116)
Show SMILES CN(C)C1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21 |r|
Show InChI InChI=1S/C21H25N/c1-22(2)19-11-12-21(15-19)14-18-9-4-3-7-16(18)13-17-8-5-6-10-20(17)21/h3-10,19H,11-15H2,1-2H3/t19?,21-/m0/s1
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.98n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assay


J Med Chem 53: 7778-95 (2010)


Article DOI: 10.1021/jm100856p
BindingDB Entry DOI: 10.7270/Q2FQ9WWQ
More data for this
Ligand-Target Pair