null

SMILES: NC(=O)c1ccc2N(CCCc2c1)c1ccc(CNC2Cc3ccccc3C2)c(Cl)c1

InChI Key: InChIKey=FVKGMUUQKBJQCS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50417598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50417598 (CHEMBL1642757) Show SMILES NC(=O)c1ccc2N(CCCc2c1)c1ccc(CNC2Cc3ccccc3C2)c(Cl)c1 Show InChI InChI=1S/C26H26ClN3O/c27-24-15-23(30-11-3-6-19-12-20(26(28)31)8-10-25(19)30)9-7-21(24)16-29-22-13-17-4-1-2-5-18(17)14-22/h1-2,4-5,7-10,12,15,22,29H,3,6,11,13-14,16H2,(H2,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by SPA				Bioorg Med Chem Lett 21: 670-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.010 BindingDB Entry DOI: 10.7270/Q2KD2051
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50417598 (CHEMBL1642757) Show SMILES NC(=O)c1ccc2N(CCCc2c1)c1ccc(CNC2Cc3ccccc3C2)c(Cl)c1 Show InChI InChI=1S/C26H26ClN3O/c27-24-15-23(30-11-3-6-19-12-20(26(28)31)8-10-25(19)30)9-7-21(24)16-29-22-13-17-4-1-2-5-18(17)14-22/h1-2,4-5,7-10,12,15,22,29H,3,6,11,13-14,16H2,(H2,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human delta opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by SPA				Bioorg Med Chem Lett 21: 670-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.010 BindingDB Entry DOI: 10.7270/Q2KD2051
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50417598 (CHEMBL1642757) Show SMILES NC(=O)c1ccc2N(CCCc2c1)c1ccc(CNC2Cc3ccccc3C2)c(Cl)c1 Show InChI InChI=1S/C26H26ClN3O/c27-24-15-23(30-11-3-6-19-12-20(26(28)31)8-10-25(19)30)9-7-21(24)16-29-22-13-17-4-1-2-5-18(17)14-22/h1-2,4-5,7-10,12,15,22,29H,3,6,11,13-14,16H2,(H2,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human kappa opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by SPA				Bioorg Med Chem Lett 21: 670-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.010 BindingDB Entry DOI: 10.7270/Q2KD2051
					More data for this Ligand-Target Pair